
Space Summit 2025
Date: Thursday, 15 May 2025 - Friday, 16 May 2025
Location: Miami, Florida
Confirmed Speakers

Alain Berinstain, Chief Strategy Officer, CSS Inc.

Emmanuel Urquieta, Vice Chair of Aerospace Medicine / Department of Medicine University of Central Florida College of Medicine

Kristin Kopperud, Science Program Director, Biological Sciences, International Space Station National Laboratory -- Conference Co-Chairperson

Maribella Domenech, Professor, Chemical Engineering, University of Puerto Rico-Mayaguez

Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory -- Conference Co-Chairperson

Ngan Huang, Associate Professor, Department of Cardiothoracic Surgery, Stanford University

Tammy Chang, Professor of Surgery, University of California-San Francisco

Arun Sharma, Associate Professor, Cedars-Sinai Medical Center

Jamie Foster, Professor, University of Florida

Lisa M. Larkin, Professor, University of Michigan

Matthew Strickland, Medical Oncologist, Director of Translational Research, Center for Space Medicine Research, MGH /Harvard Medical School

Molly Mulligan, Director, Business Development, Redwire

Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham

Tobias Niederwieser, Assistant Research Professor, BioServe Space Technologies

Chunhui Xu, Professor, Emory University School of Medicine

Kenneth A. Savin, Chief Scientist - Redwire

Mari Anne Snow, CEO and Co-Founder, Eascra Biotech

Meghan Everett, Deputy Chief Scientist, International Space Station

Natalia Tumidajski, Principal Scientist, GMP Site Head, EXOCEL BIO INC.

Rihana Bokhari, Scientific Research Director at the Translational Research Institute for Space Health (TRISH)

Yupeng Chen
Associate Professor, University of Connecticut
Overview
The Space Summit 2025 will be held May 15-16, 2025 right at the Embassy Suites Miami International Airport.
This conference venue provides very easy access from around the world via Miami International Airport a FREE Shuttle ride away (airport code: MIA).
Space Summit 2025 brings together researchers who have sent research payloads aboard the international space station (ISS) as well as researchers seeking to send their research into microgravity on-board the ISS.
Additionally, the impact of the private space stations coming online in low earth orbit (LEO) will be assessed from the standpoint of pricing and access to researchers.
The conference is co-chaired by Dr. Mike Roberts, Chief Scientific Officer and Dr. Kristin Kopperud, Science Program Director-Biological Sciences, International Space Station National Laboratory -- the Chairpersons will set the tone of the conference plus provide actionable information to researchers seeking to expand their research into LEO.
Speakers and Delegates are composed primarily of researchers involved in various disciplines that are amenable to LEO such as Organs-on-Chips in Space, Tissue-Chips, Organoids, 3D-Printing, Flow Chemistry-Space Chemistry, amongst others.
Additionally, platform and infrastructure providers who are critical in providing the correct form factor as well as telemetry ob-board station will be present to provide practical guidance to researchers seeking LEO for their research.
Registered delegates will have full access to the co-located and concurrent conference track to mix-and-match presentations and maximize networking:
Extracellular Vesicles (EVs) and Lipid-Nanoparticles (LNPs) gaining attention and amenable to research in LEO. In fact, NCATS is putting out a RFP for EVs in Space.
There are ample opportunities for networking, partnering and business development at this conference and this ensures a very cost-effective conference trip.
The Exhibit Hall is Co-Located with the Conference Tracks for Excellent Networking with the various vendors and platform providers.
Call for Oral Presentations and Posters
Agenda Topics
You can also present your research in an oral presentation or poster while attending the meeting. Submit an abstract for consideration now!
Poster Submission Deadline: February 28, 2025.
- • 3D-Bioprinting in Orbit
• 3D-Organoid Models for Disease in Microgravity Conditions
• Effect of Microgravity on Drug Responses
• Flow Chemistry - Chemistry in Space
• Organs-on-Chips as a Platform for Studying Effects of Microgravity on Human Physiology
• Tissue Chips in Space NIH/NCATS-ISS US National Laboratory Projects
• Research Projects in Low Earth Orbit (LEO)
• Private Space Stations offering Commercial Access to LEO for Research, Development and Manufacturing
• Platform Providers Offering Access to LEO for Scientific Research Projects
Sponsorship and Exhibition Opportunities
Jeff Fan
Exhibition Manager - SelectBIO
E-mail: Jeff@selectbioconferences.com
3 for 2 Offer on Delegate Registrations
SelectBIO are offering 3 Delegate Registrations for the price of 2 on all delegate passes. To take advantage of this offer, please contact us by email, phone or click the Contact Us button below. Looking for more than 3 Delegate Passes? Contact us for more information on our special rates for large groups.
Any questions or assistance during registration, please call us at: +1 (510) 857-4865 or e-mail us at: Contact SelectBIO
Gold Sponsors
Exhibitors
Sponsorship and Exhibition Opportunities
If you require any information about exhibiting or sponsoring at one of our events please contact Jeff Fan using the information below:
Jeff Fan, Exhibition Manager
Email: jeff@selectbioconferences.com
Telephone: +1-510-857-4865
Why exhibit at a SELECTBIO show?
Specialists: SELECTBIO doesn't organise conferences in shipping, accountancy, textiles etc. – just drug discovery and the life sciences. Many of our staff have bioscience qualifications and many years of experience. So, we speak your language and understand your needs.
Superior Customer Service: Our sales team will take care of you with specialist advice and customised packages. We don’t forget you after you sign on the bottom line either as our customer service dept. will alert you to all the things you need to think about up to and during the event itself.
Networking: Pre-Event, During and Post-Event you can communicate electronically with all other attendees either using our U-NETWORK system from your PC or via our exclusive new app
Free Lead Retrieval System: Why pay a small fortune for a third party system? SELECTBIO empower you to do this yourself with the badge scanner built into our new app using your smartphone or tablet.
The Space Summit 2025 Conference Venue
SelectBIO is delighted to host The Space Summit 2025 at the:
Embassy Suites by Hilton Miami International Airport
3974 NW South River Drive
Miami, FLORIDA 33142
USA
SelectBIO has negotiated discounted hotel rates for stay at this venue at the pricing of US$149 per night (2 Room Suite - 1 King Bed).
The cut-off date for this discounted pricing is April 12, 2025 -- so please make your hotel booking prior to this date to lock-in the discounted pricing.
Check-in 4pm
Check out 11am
Complimentary Miami Airport Shuttle
Complimentary Full Cooked Breakfast
Complimentary Evening Reception with Wine and Beer
Complimentary Wi-Fi
Overnight Self-Parking US$10 per night
Once you click the green button below, a new webpage dedicated to the conference venue hotel will open up and will provide you with the discounted conference delegate pricing. At this point, please proceed to type in the dates required, and complete the booking process.
To make your Hotel Reservations Online:




For any hotel reservation-related issues, or if you need any help with hotel bookings, please contact:
Jeff Fan
Events Manager, SelectBIO
E-mail: Jeff@selectbioconferences.com
SelectBIO has NOT authorized ANY third party company to assist in hotel bookings or reservations for the conference. Please do NOT do business with any third party companies. If in doubt, please contact Jeff Fan immediately to clarify.
Register to this conference and also enjoy the following co-located events at no extra charge.
Training Courses
If you would like to submit a proposal for an oral or poster presentation at this meeting, please fill out the form below required for your submission.
Successful applicants will be provided with all necessary information.
Abstract Content:
-
Written in English
-
Written in the third person
-
Include title, name(s) and affiliation(s) of the authors
-
Between 100 - 200 words
-
Suitable for direct publication in the proceedings pack and on the website
-
Related to the subject of the conference
Agenda Topics
- • 3D-Bioprinting in Orbit
• 3D-Organoid Models for Disease in Microgravity Conditions
• Effect of Microgravity on Drug Responses
• Flow Chemistry - Chemistry in Space
• Organs-on-Chips as a Platform for Studying Effects of Microgravity on Human Physiology
• Tissue Chips in Space NIH/NCATS-ISS US National Laboratory Projects
• Research Projects in Low Earth Orbit (LEO)
• Private Space Stations offering Commercial Access to LEO for Research, Development and Manufacturing
• Platform Providers Offering Access to LEO for Scientific Research Projects
Copyrights
The presenting author/person who submitted the abstract assumes full responsibility of the content of the abstract and we assume that all co-authors are aware of this content. Please note that your biography, summary and abstract may be used on this website and conference materials.
Alain Berinstain, Chief Strategy Officer, CSS Inc.

Alain Berinstain Biographical Sketch
As Chief Strategy Officer, Dr. Berinstain is responsible for leading CSS’s overall corporate strategy, driving business growth and overseeing new space initiatives. Dr. Berinstain has been a thought leader in the space industry for over 25 years, most recently as Chief Strategy Officer at Space Tango and earlier as Vice President of Moon Express, developing their customer base and growth strategies. Prior to working in the commercial space sector in the US, Alain was at the Canadian Space Agency, acting in several executive positions, during which time he played leadership roles in international space cooperation groups. He has developed payloads and instrumentation with world-class scientists for missions on the Space Shuttle, Space Station Mir, the International Space Station, and a number of other space missions. Alain has a Bachelor’s degree in Chemistry and Biochemistry and a PhD in Physical Organic Chemistry; he also has a Masters of Space Studies from the International Space University.
Arun Sharma, Associate Professor, Cedars-Sinai Medical Center

Arun Sharma Biographical Sketch
Dr. Arun Sharma, PhD is a stem cell biologist focusing on cardiovascular biology and space biosciences. He is an associate professor at Cedars-Sinai and is affiliated with the Board of Governors Regenerative Medicine Institute, the Smidt Heart Institute, the Cancer Institute, and the Department of Biomedical Sciences.
Research in the Sharma laboratory focuses on the applications of human induced pluripotent stem cells (hiPSCs) for modeling cardiovascular diseases outside of the body (in-vitro). The lab utilizes cutting-edge technologies including hiPSCs, genome editing, cardiac organ-on-chips, and 3D cardiac spheroids/organoids to understand the molecular mechanisms driving cardiovascular disease and heart development. For example, the Sharma laboratory employs hiPSC-derived cardiomyocytes (personalized, beating heart muscle cells) to develop novel ways to alleviate the cardiovascular damage caused by cancer drugs. The lab also studies the developmental mechanisms underlying congenital heart disease, as well as examines the impact of infections on the cardiovascular system, such as in the setting of COVID-19.
Sharma also has a unique background and interest in the space biosciences and investigates means by which stem cell biology can intersect with this emerging field. In 2016, Dr. Sharma led a project that sent human stem cell-derived heart cells to the International Space Station to study the effects of microgravity on human heart function, which was the first long-duration cell culture experiment in space. He remains an internationally-recognized leader in the space biosciences field, and his laboratory studies means of harnessing microgravity to manufacture unique biomaterials.
Sharma has published articles in leading scientific journals such as Science, Nature Biotechnology, Science Translational Medicine, Circulation Research, Nature Reviews, Stem Cell Reports, and Cell Stem Cell. His research has been featured in major news outlets such as Forbes Magazine, Newsweek, Science Magazine, and the Wall Street Journal. He has received numerous awards for his work, including the Forbes 30 Under 30 in Science, STAT Wunderkinds, Sartorius & Science Award in Regenerative Medicine, the American Heart Association Career Development Award, the Compelling Results Award from NASA, and the Donna and Jesse Garber Award for Cancer Research.
Chunhui Xu, Professor, Emory University School of Medicine

Chunhui Xu Biographical Sketch
Chunhui Xu, Ph.D., is a Professor in the Department of Pediatrics, Emory University School of Medicine. Dr. Xu has extensive research experience on stem cells and heart cell development. Her research is focusing on heart cells derived from human pluripotent stem cells (hPSCs), which hold promise for cell therapy, disease modeling, and drug discovery. Her group has made significant contribution to the field of hPSCs. Several of their publications have been identified as a hot paper or among the most highly cited publications in the field of hPSCs. She is an inventor or co-inventor of 18 issued US patents, and her publications have been cited more than 12,000 times according to Google Scholar. Her research has been funded by NCI, NHLBI, NIAAA, NSF, CASIS, AHA, and HESI/FDA. Her spaceflight experiment was called as a significant step for next-generation space research by the International Space Station National Laboratory, and featured by CNN, NASA, and Chemical & Engineering News.
Emmanuel Urquieta, Vice Chair of Aerospace Medicine / Department of Medicine University of Central Florida College of Medicine

Emmanuel Urquieta Biographical Sketch
Emmanuel Urquieta, M.D., M.S., FAsMA, is the Vice Chair of Aerospace Medicine and Associate Professor of Medicine at the University of Central Florida – College of Medicine. In his role at UCF, he oversees the development of research, education, and partnerships in the domain of aerospace medicine. Prior to joining UCF, Dr. Urquieta served as the Chief Medical Officer at the NASA-funded Translational Research Institute for Space Health where we managed a multimillion-dollar portfolio of medical research for missions to the Moon and Mars, the commercial spaceflight program EXPAND, and analog capabilities, including partnerships with the Australian Antarctic Division. Dr. Urquieta has extensive experience providing medical care in austere and remote environments serving as a flight surgeon in Mexico City’s Police Department Helicopter Emergency Medical Services, participating in hundreds of rescue missions and aeromedical evacuations. He has volunteered in medical missions around the world. In 2017, Dr. Urquieta was selected as a crew member of the Human Exploration Research Analog (HERA) XI mission at NASA Johnson Space Center, spending 30 days in a capsule simulating a deep space long-duration mission. He is a Fellow of the Aerospace Medical Association, and an academician of the International Academy of Astronautics, and has authored and co-authored dozens of publications in peer-reviewed scientific journals. Dr. Urquieta holds a medical degree and specialty in emergency medicine from Anahuac University in Mexico City and an M.S. in aerospace medicine from Wright State University in Dayton, Ohio.
Jamie Foster, Professor, University of Florida

Jamie Foster Biographical Sketch
Dr. Foster’s role in the Astraeus Space Institute has been to build stronger connections between the Florida Space Coast, including the rapidly expanding commercial space industry, and the University of Florida. Dr. Foster is the lead contact for the Space Edge Accelerator UF Hub, a program to help new companies learn about expanding their space biomanufacturing portfolio and building connections with space implementation partners and launch providers. Dr. Foster is also the UF site lead for the Center for Science, Technology, and Research in Space (C-STARS). C-STARS is an NSF-funded program that brings academic researchers across the State of Florida together with spaceflight providers to help industries transition to the space manufacturing sector and improve the production of unique medicines, therapeutics, and materials that can benefit the people of Earth. Dr. Foster’s long-term goal for the University of Florida Astraeus Space Institute is to serve as a centralized hub for collaborations between researchers and commercial companies providing critical access, experience, and knowledge to increase research and production capabilities in the space environment.
Kenneth A. Savin, Chief Scientist - Redwire

Ken Savin Biographical Sketch
After receiving his PhD from the University of Utah in synthetic organic chemistry, Dr Kenneth Savin did a post doc at the Memorial Sloan Kettering Cancer Center before going on to work for Eli Lilly and Co. as a senior research scientist. During his 20-year career in the pharmaceutical industry, Ken led discovery chemistry research teams, discovery operations, radiochemistry, drug disposition, chemistry development and product teams as well as being an adjunct faculty member at Butler University. During the last four years of Ken’s industrial career, he led an effort that resulted in five separate flight experiments flown on the International Space Station. After retiring from Lilly, he joined the team at the Center for the Advancement of Science In Space (CASIS) (the operators of the International Space Station National Lab) working in both Business Development, as a science lead and ultimately as the Sr. Director of In Space Production Applications. During his time at CASIS, Ken worked with a team at NASA to develop the In Space Production and Applications program that is run out of NASA as an effort to develop products in space that will benefit life on the Earth. Ken joined the Redwire team in early 2022 to be the Chief Scientific Officer at Redwire. His focus at Redwire has been on the commercialization of work performed in the labs at Redwire and in developing partnerships that will lead to better products and easier access to the value that space based products can provide.
Kristin Kopperud, Science Program Director, Biological Sciences, International Space Station National Laboratory

Kristin Kopperud Biographical Sketch
Dr. Kristin Kopperud joined the Center for the Advancement of Science in Space, Inc. (CASIS), which manages the International Space Station (ISS) National Laboratory, as an Operations Project Manager in June 2020. She transitioned to the role of Science Program Director of Biological Sciences in the Research and Innovation department in March 2022. Her focus areas include tissue engineering, in-space production applications and biomanufacturing, and rodent research. In this role, she works with Principal Investigators to outline their science requirements during the early stages of their projects’ lifecycles. Using skills developed in her former role in the Operations department, she is able to evaluate concepts and proposals from an operational standpoint as well as a scientific one, which helps her to refine the projects’ requirements to feasibly support biology in microgravity. She also works with the Education department to use science as a means of education and outreach and presents to the public in webinars and conferences to connect to researchers in microgravity and beyond.
Dr. Kopperud received her BS in Biotechnology and Biology from the University of Kentucky. She earned her PhD in Biological Sciences from Florida Institute of Technology in Melbourne, FL studying circadian rhythms in the retina of the Atlantic tarpon. While she moved to Florida to pursue a career in marine biology, she was captivated by the space culture that was inescapable on the Space Coast. During graduate school, she taught undergraduate laboratory sections of Mammalian Physiology and Biology and was recruited to serve as a Research Support Scientist for several ISS National Lab-sponsored Rodent Research missions, serving as a surrogate for the crew on the ISS. Thus began a career in the aerospace industry—and she hasn’t looked back!
Lisa M. Larkin, Professor, University of Michigan

Lisa Larkin Biographical Sketch
Lisa M Larkin, PhD, is a Professor of Molecular & Integrative Physiology at the University of Michigan. She holds a joint appointment in the Biomedical Engineering Department at the University of Michigan. Dr. Larkin is the director of the Skeletal Tissue Engineering Laboratory at the University of Michigan and has 35 years of expertise on musculoskeletal physiology and small and large animal surgical procedures and more than 21 years’ experience specifically with ligament, tendon, muscle, and bone tissue engineering. Larkin has pioneered methods to co-culture scaffold-free tissue constructs to engineer functional tissues and their interfaces. Dr. Larkin has five patents and two pending patents for her work. She has co-authored 44 peer-reviewed journal papers on tissue engineering, 4 reviews and two book chapters specifically on tissue engineering, another 33 on the physiology of muscle. Dr. Larkin is a member of the following societies: The American Physiological Society, Society for Neuroscience, Tissue Engineering International and Regenerative Medicine Society, Biomedical Engineering Society, and Orthopaedic Research Society.
Mari Anne Snow, CEO and Co-Founder, Eascra Biotech

Mari Anne Snow Biographical Sketch
Mari Anne Snow is the CEO and co-founder of Eascra Biotech, an early-stage nanomedicine startup leveraging low Earth orbit (LEO) to accelerate the development of advanced therapeutics for the benefit of patients on Earth. Eascra is a participant in NASA's In Space Manufacturing (InSPA) Program and a recipient of the ISS National Lab® Igniting Innovation Award. The Eascra team has successfully sent samples to the ISS on Ax2, NG-20, and SpX-30, and is scheduled to continue their rapid progress with payloads on the upcoming SpX-31 and SpX-32 missions.
Maribella Domenech, Professor, Chemical Engineering, University of Puerto Rico-Mayaguez

Maribella Domenech Biographical Sketch
Dr. Maribella Domenech is a distinguished Puerto Rican scientist and full-time Professor in the Department of Chemical Engineering at the University of Puerto Rico-Mayagüez (UPR-Mayagüez). She earned her B.S. in Industrial Biotechnology from UPR-Mayagüez (2006), followed by an M.S. and Ph.D. in Biomedical Engineering from the University of Wisconsin-Madison (2010), and completed her postdoctoral training in Chemical Engineering at UPR-Mayagüez (2012).
For the past 12 years, Dr. Domenech has been an independent researcher and educator specializing in the development of biomaterials and cell culture platforms to model the breast tumor microenvironment and enhance the potency of therapeutic cells in manufacturing processes. She is a key member of several research leadership teams, including the NSF-Sponsored Engineering Research Center in Cell Manufacture Technologies (CMAT) and the Center for the Advancement of Wearable Technologies (CAWT).
Her work has been showcased at over 30 conferences, and she has authored more than 20 peer-reviewed journal articles along with contributing two book chapters. Dr. Domenech’s research and mentorship have been recognized with numerous awards, including the Industrial Biotechnology Alumni Role Model Award (2015–2017), the Faculty Cancer Research Award from the American Association for Cancer Research (2016), the Distinguished Engineer Faculty Award (2018), and most recently, the 2024 AACR Minority and Minority-Serving Institution Faculty Scholar in Cancer Research Award and the Research Investigator of the Year for the UPR eleven-campus system.
Notably, Dr. Domenech is the first female engineering faculty member from the UPR system to be elected as a standing member of the Cellular and Molecular Technologies Study Section at the NIH Center for Scientific Review. She is also the first scientist—and female—to send cell culture technologies to space from Puerto Rico, aboard the SpaceX-31 mission. Recently, she was recognized by Engineering Now Magazine as one of the most outstanding female engineering researchers at UPR-Mayagüez and by Ciencia Puerto Rico as one of the top 37 Puerto Rican females in STEM, earning her a place in the “Borinqueñas in STEM” exhibit at the Centro Criollo de Ciencias y Tecnología del Caribe (C3Tec).
Matthew Strickland, Medical Oncologist, Director of Translational Research, Center for Space Medicine Research, MGH /Harvard Medical School

Matthew Strickland Biographical Sketch
Dr. Strickland is a medical oncologist at Massachusetts General Hospital and an Instructor in Medicine at Harvard Medical School. He completed his internal medicine training at Boston Medical Center followed by Hematology and Oncology fellowship training at the Dana Farber Cancer Institute, Massachusetts General Hospital and Brigham and Women’s hospital. He is board certified in Internal Medicine and Medical Oncology and belongs to several oncology research organizations including American Society of Clinical Oncology (ASCO) and American Association of Cancer Research (AACR). His work has been published in multiple journals including Cancer Discovery, Nature Communications and Clinical Cancer Research. As a medical oncologist within the multidisciplinary gastrointestinal oncology group at MGH, Dr. Strickland works with other specialists such as surgeons, radiation oncologists and others to develop personalized, cutting edge therapeutic plans for patients. His research focus includes developing clinical trials to discover better therapies and improve outcomes for patients with GI cancers. As Director of Translational Research at the Center for Space Medicine Research at MGH, his group works towards leveraging the unique research environment of microgravity to discover better therapies for patients living with cancer. Originally from Alberta, Canada, he is an avid ice hockey fan, enjoys flying as a private pilot and diving as a certified SCUBA diver.
Meghan Everett, Deputy Chief Scientist, International Space Station

Meghan Everett Biographical Sketch
Dr. Meghan Everett support research across a variety of technical areas for the International Space Station. She started her NASA career in 2007 in the exercise physiology laboratory and conducted several ISS and analog research experiments focusing on human performance and optimizing crew health for ISS and exploration missions. Prior to her current position Meghan provided crew health support as the ISS Program Crew Health and Countermeasures System (CHeCS) Integrator. Meghan obtained a BS degree from Skidmore College in Exercise Physiology, and MS and PhD from University of Houston in kinesiology with a focus in molecular muscle physiology.
Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory

Michael Roberts Biographical Sketch
Michael S. Roberts, PhD is the Chief Scientific Officer of the International Space Station National Laboratory, managed by the Center for the Advancement of Science in Space, Inc. (CASIS). Before joining CASIS in 2013, Michael worked as a principal investigator and research group lead in the NASA Advanced Life Support program at the Kennedy Space Center. Prior to arriving at NASA-KSC in 1999, Michael completed an undergraduate degree in biology at Maryville College, a doctorate in microbiology at Wesleyan University and post-doctoral research at the Center for Microbial Ecology at Michigan State University and the RIKEN Institute in Wako-shi, Japan.
Molly Mulligan, Director, Business Development, Redwire

Molly Mulligan Biographical Sketch
Dr. Molly Mulligan is director of business development at Redwire’s In Space Manufacturing and Operations business unit. In this role, she supports business development efforts for the company’s biotechnology and materials science portfolio.
Prior to joining Redwire, Dr. Mulligan worked at Space Commerce Matters as the Director of Commercialization Strategies, where she led efforts in commercial allocation and commercialization strategies. In 2017, Dr. Mulligan returned to the United States and began working for the Center for the Advancement of Science in Space (CASIS). CASIS manages the US National Lab located on the International Space Station (ISS).
In 2014, Dr. Mulligan’s expertise in the area of tissue chips led her to join SpacePharma, a start-up company in Herzliya Israel, that builds hardware for research platforms based in space.
Dr. Mulligan did her post-doctoral work in Biomedical Engineering at the Technion - Israel Institute of Technology. At the Technion, Dr. Mulligan’s work focused on tissue chips, this time looking at breathing lung models. Dr. Mulligan attended the University of Massachusetts Amherst (UMass), where she earned a PhD in Mechanical Engineering in 2011, and Smith College ('05), where she double majored in Physics and Astronomy.
Natalia Tumidajski, Principal Scientist, GMP Site Head, EXOCEL BIO INC.

Natalia Tumidajski Biographical Sketch
Natalia Tumidajski is a Principal Scientist and GMP Site Head at ExoCel Bio in Doylestown, Pennsylvania with a background in regenerative medicine, stem cell research, and exosome technology, Her work focuses on developing innovative solutions for skin health, anti-aging, hair rejuvenation, and wound healing. In her current role, Natalia leads the development and management of a state-of-the-art facility specializing in regenerative medicine. She oversees GMP and R&D laboratories, ensuring compliance with regulatory standards and driving innovative research initiatives. Her leadership extends to strategic site management, experimental design, and the development of novel products. Natalia is also an active presenter at national conferences, sharing her findings and contributing to the scientific community.
Natalia’s lab is dedicated to optimizing GMP manufacturing of exosomes, conducting in-depth characterization studies—including mRNA and growth factor expression profiling—and assessing the effects of lyophilization on extracellular vesicle stability. The team is also evaluating advanced 3D cell culture systems and exploring the effects of microgravity and hypoxia on exosome yield and potency, aiming to enhance their therapeutic potential for regenerative medicine.
Ngan Huang, Associate Professor, Department of Cardiothoracic Surgery, Stanford University

Ngan Huang Biographical Sketch
Ngan F. Huang is an Associate Professor in the Department of Cardiothoracic Surgery at Stanford University and Research Career Scientist at the Veterans Affairs Palo Alto Health Care System. Dr. Huang completed her BS in Chemical Engineering from the Massachusetts Institute of Technology, followed by a PhD in bioengineering from the University of California Berkeley & University of California San Francisco Joint Program in Bioengineering. Prior to joining the faculty, she was a postdoctoral scholar in the Division of Cardiovascular Medicine at Stanford University. Her laboratory investigates the interactions between stem cells and extracellular matrix microenvironment for engineering cardiovascular tissues to treat cardiovascular and musculoskeletal diseases. Recent research focuses on the role of microgravity for drug screening of engineered muscle tissue for reversing aging and atrophy. Dr. Huang has authored over 100 publications and patents, including those in Nat Med, PNAS, and Circ Res. She has received numerous honors, most recently including the Society for Biomaterials Mid-Career Award, the Alan Hirsch Mid-Career Award in Vascular Medicine from the American Heart Association, and the inaugural Elena Aikawa Trailblazer award from the International Society for Applied Cardiovascular Biology. She has been inducted as a fellow of the American Heart Association as well as the American Institute for Medical and Biological Engineering. She has active or completed projects funded by the National Institutes of Health, National Science Foundation, American Heart Association Department of Defense, California Institute of Regenerative Medicine, and Department of Veteran Affairs.
Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham

Palaniappan Sethu Biographical Sketch
Dr. Palaniappan Sethu is a Biomedical Engineer by training with a PhD from the University of Michigan where he developed new polymer based lab-on-a-chip technologies for genomic and proteomic assays. Dr. Sethu completed his postdoctoral training at the Center for Engineering in Medicine at Massachusetts General Hospital, Harvard Medical School and Shriners Burns Hospital working on label-free approaches to isolate leukocyte sub-populations from whole blood. After spending the 1st 7 years of his career at the University of Louisville, he is currently a Professor of Medicine and Biomedical Engineering within the Division of Cardiovascular Disease at the University of Alabama-Birmingham. Dr. Sethu also serve as the Section Chief for Basic and Translational Sciences within the Division of Cardiovascular Diseases and as the Program Director for the Engineering Education in Medicine Program within the Department of Biomedical Engineering.
Rihana Bokhari, Scientific Research Director at the Translational Research Institute for Space Health (TRISH)

Rihana Bokhari Biographical Sketch
I am a space physiologist with experience in bone biology, radiation biology and additional expertise in science management, portfolio management, solicitation writing and review. I began my PhD work with a fascination for space life sciences, though it was a new area for me as I grew up far from a NASA center. I was fortunate to earn a National Space Biomedical Research Institute fellowship during my first few years of graduate work that allowed me to become up to speed with the space research world. This fellowship led me to earning a certification in Space Life Sciences and several NASA internships that have helped me to develop a well rooted understanding of Space Health as well as NASA priorities in these areas.
I am currently the Scientific Research Director for the Translational Research Institute for Space Health (TRISH). I have faculty appointments in Baylor College of Medicine’s Center for Space Medicine and the Department of Education, Innovation and Technology. My primary expertise lies in the effects of disuse and radiation on the musculoskeletal system. I lead the TRISH Science Office honing and implementing our science strategy through solicitation design, recommending proposal selection, interfacing with awarded investigators, and translating the findings from TRISH projects back to NASA. I most recently served as the Acting Chief Scientific Officer (CSO) for TRISH where I focused on continuing the develop and implement TRISH’s scientific strategy and the Deputy CSO where I supported the CSO in leading the TRISH Science Office. I have previously served as a support scientist at the NASA Research and Education Support Services, where I focused on facilitating grant review, solicitation writing, project management, and portfolio management for not only TRISH but also the NASA Space Biology Program and the NASA Human Research Program.
Tammy Chang, Professor of Surgery, University of California-San Francisco

Tammy Chang Biographical Sketch
Dr. Tammy T. Chang is Professor of Surgery at the University of California, San Francisco (UCSF). She holds an M.D.-Ph.D. combined degree from Harvard Medical School, and her clinical training includes General Surgery Residency and Minimally Invasive Surgery Fellowship at UCSF. Dr. Chang attends on the Acute Care Surgery service at UCSF Medical Center, and she directs a basic and translational research laboratory focused on liver tissue engineering. The unifying theme of her research program is to understand how physical conditions, including dimensionality and extracellular matrix, regulate hepatocyte function. Overarching goals of Dr. Chang’s laboratory are to develop novel tissue-based therapies to treat severe liver dysfunction and to advance bench-to-operating-room regenerative surgery approaches. Accordingly, her work has delineated the role of stiffened matrix in fibrotic liver disease, characterized the function of human stem cell-derived liver organoids, and investigated microgravity-enabled cellular self-assembly in generating larger tissue constructs. Extramural support for Dr. Chang’s research includes sources from the NIH, NSF, NASA, Open Philanthropy, and the American College of Surgeons.
Tobias Niederwieser, Assistant Research Professor, BioServe Space Technologies

Tobias Niederwieser Biographical Sketch
Tobias Niederwieser is an Assistant Research Professor at BioServe Space Technologies within the University of Colorado Boulder where he serves as Principal Investigator on several grants for space life science experiments. Of particular focus is the in-space manufacturing of human pluripotent stem cells for regenerative therapy applications on Earth. Previously, he led the development of several novel facilities operating continuously onboard the ISS including science incubators, centrifuges, life support systems, as well as crew galley refrigerators that have enabled experiments on over 40 orbital launches. He is currently developing similar facilities for commercial and lunar space stations. Additionally, Tobias was involved in the DSRG radiation biology experiment onboard Artemis-I conducting the furthest active biology experiment with sample return ever performed.
Yupeng Chen, Associate Professor, University of Connecticut, United States of America

Yupeng Chen Biographical Sketch
Dr. Yupeng Chen is an Associate Professor in the Department of Biomedical Engineering at the University of Connecticut. Holding both an M.Sc. and a Ph.D. in biomedical engineering and chemistry from Brown University, Dr. Chen's long-term research interest lies in the design and development of DNA-inspired Janus base nanomaterials for regenerative engineering applications. He holds 11 US patents and 14 international patents in Janus base nanotechnology, some of which have been successfully licensed to industry partners. Dr. Chen has authored one book, 11 book chapters, and 74 peer-reviewed publications, and he and his lab have delivered 127 conference presentations and invited talks. His achievements have been recognized with the Faculty Early Career Development (CAREER) award from NSF, the discovery award from DOD, and the New Investigator Recognition Awards from the Orthopaedic Research Society. Elected as a senior member of the National Academy of Inventors (NAI) and a member of the Connecticut Academy of Science and Engineering (CASE) in recognition of his efforts to translate scientific breakthroughs into practical applications, Dr. Chen has secured many competitive federal research grants from agencies such as NIH, NSF, NASA, DOD, and the International Space Station (ISS) National Lab.
08:00
15 May 2025
Grand Ballroom Foyer
Conference Registration, Materials Pick-Up, Coffee and Networking
09:00
15 May 2025
Bimini
Welcome and Introduction to the Conference by Conference Co-Chairpersons:
Dr. Kristin Kopperud, Science Program Director, Biological Sciences, International Space Station National Laboratory
Dr. Michael Roberts, Chief Scientific Officer, International Space Station National Laboratory
09:15
15 May 2025
Bimini

Meghan Everett, Deputy Chief Scientist, International Space Station, United States of America
NASAs International Space Station (ISS) Science Overview
This presentation will provide an overview of the science areas and capabilities for research on ISS. Novel and innovative results of exemplary ISS research will also be highlighted.
09:45
15 May 2025
Bimini
Matthew Wallace, NASA In-Space Production Applications (In-SPA)
Session Sub-Title: BioManufacturing in Space and Other Commercial Activities in Low Earth Orbit (LEO)
10:15
15 May 2025
Bimini
Nicole Wagner, CEO, Lambda Vision
Title to be Confirmed
10:45
15 May 2025
Coconut Grove
Mid-Morning Coffee Break and Networking with Exhibitors
11:15
15 May 2025
Bimini

Maribella Domenech, Professor, Chemical Engineering, University of Puerto Rico-Mayaguez
Advancing Microcarrier-Based Culture Systems for Space Studies and Biomanufacturing of Mesenchymal Stem Cells
Understanding how microgravity alters cell behavior is essential for advancing stem cell-based biomanufacturing both in space and on Earth. Our recent studies aboard the SpaceX CRS-31 mission use mesenchymal stem cells (MSCs) cultured on bioactive microcarriers to investigate how a low-shear, convection-free environment impacts cell-matrix interactions and the anti-inflammatory potency of secretomes. Although microcarrier-based culture systems are well-established on Earth, adapting them for space research is a novel endeavor. Our work demonstrates that microcarrier cultures can be successfully deployed in microgravity. These pioneering results underscore the potential of this technology to advance MSC studies and scale up biomanufacturing in space. In this presentation, we will discuss our microcarrier-based culture system, share our latest findings from space, and explore how these insights pave the way for developing cell models and therapies that benefit life on Earth.
11:45
15 May 2025
Bimini

Mari Anne Snow, CEO and Co-Founder, Eascra Biotech, United States of America
Building High Performing Multi-discipline Teams to Develop Advanced Medicines in Space
Building a thriving space economy that can cost-effectively support the commercial production of medicines, advanced materials and other cutting-edge technologies in space requires a multi-disciplinary, highly collaborative team laser-focused on shared goals. In this real-world use case discussion, Mari Anne will outline the best practices her team adopted, enabling them to complete three successful missions in less than a year, despite being new to spaceflight.
12:15
15 May 2025
Havana

Natalia Tumidajski, Principal Scientist & GMP Site Head, ExoCel Bio, Pennsylvania Biotechnology Center, United States of America
Space Microgravity and Hypoxia Conditions as a Novel Approach to Enhance Regenerative Potency of MSC-derived Exosomes in Specialized 3D Cell Culture System
Research in microgravity is emerging as a new approach in studying biological systems and designing better treatment options. Recent studies in space have shown that microgravity transforms the behavior of stem cells and has unparallel effects on their growth, proliferation, and secretion of bioactive molecules such as extracellular vesicles. Regardless of continuous advancements in stem cell-based therapies, there are still significant challenges to ensure reproducibility, stability, and maximized potency for biomedical applications. Universal 2D cell culture system fails to mimic a natural environment for stem cells limiting their full capabilities including reduced stemness and deficient cell to cell interactions. Our approach was to create a natural niche for mesenchymal stem cells where they can cultivate their full biological potential and release the most potent exosomes- significant meditators in cell-to-cell communication via enriched cargo of proteins, lipids, and mRNAs. In this study, using placental MSCs we generated 3D cell models- spheroids with 5th dimensional technology and hydrogel-based organoids. They were then cultured in bioreactors in specialized 3D systems using microgravity, hypoxia, and rotational speed as the main conditions to mimic unique space environment. Upon isolation of exosomes from conditioned media the comprehensive characterization was conducted to validate their enhanced biological activity and regenerative potential. This completely novel and innovative study could ignite a cutting-edge revolution for regenerative applications such as wound healing, tissue engineering, and organ regeneration.
12:45
15 May 2025
Atrium
Networking Lunch in the Atrium
13:45
15 May 2025
Bimini

Kenneth A. Savin, Chief Scientist - Redwire, United States of America
Crystals and Commerce in Space
We will present results demonstrating the difference in crystals formed terrestrially vs those generated on the International Space Station Platform and describe the use of those crystals as seeds for future terrestrial production of pharmaceuticals.
14:15
15 May 2025
Bimini
Session Sub-Title: Stem Cells in Space Under Microgravity Conditions
Session Chair: Dr. Davide Marotta, Science Program Director, ISS-National Laboratory
14:30
15 May 2025
Bimini
Jessica Pham, Mission Specialist, Sanford Stem Cell Institute, United States of America
Title to be Confirmed
15:00
15 May 2025
Bimini

Arun Sharma, Associate Professor, Cedars-Sinai Medical Center, United States of America
Stem Cell Modeling and Biomanufacturing in Space
With extended stays in space becoming commonplace, there is a need to better understand the effects of microgravity and spaceflight on cellular function. Recent work by our lab has utilized human induced pluripotent stem cells (hiPSCs) to study the effects of spaceflight-induced microgravity on the cells of the human body. We will also discuss using improved multilineage model systems (organ-chips, organoids) to explore new possibilities associated with stem cell-based biomanufacturing in space.
15:30
15 May 2025
Bimini

Chunhui Xu, Professor, Emory University School of Medicine, United States of America
Heart Stem Cells: Disease Modeling and the Impact of Space Microgravity
Cardiomyocytes derived from human induced pluripotent stem cells have created a new paradigm for modeling heart disease, testing drug response, and improving cardiac regeneration. In this talk, I’ll provide specific examples on the application of these cells. I’ll also discuss new technologies to facilitate the application of these cells including our findings on the effect of space microgravity on cardiomyocytes.
16:00
15 May 2025
Coconut Grove
Mid-Afternoon Coffee Break and Networking in the Exhibit Hall
16:30
15 May 2025
Bimini

Tobias Niederwieser, Assistant Research Professor, BioServe Space Technologies, United States of America
Scaling Up Stem Cell Manufacturing in LEO
Multiple efforts are currently underway to biomanufacture various kinds of stem cell products in space including reprogramming, expansion, and differentiation at micro to milliliter levels. BioServe has developed protocols and flown a novel bioreactor that allows larger scale and more automated manufacturing. We are currently investigating its use for induced pluripotent and hematopoietic stem cell production in a variety of use cases for developing clinical therapies on Earth.
17:00
15 May 2025
Bimini
Round-Table Discussion Hosted by Dr. Kopperud and Dr. Roberts:
How to Get Your Research Payload On-Board the International Space Station (ISS) - National Laboratory?
Meg Everett, Derek Duflo, Yupeng Chen, Nicole Wagner, Chunhui Xu, Ngan Huang
18:00
15 May 2025
Atrium
Networking Reception with Beer & Wine
19:00
15 May 2025
Atrium
Close of Day 1 of the Conference
08:00
16 May 2025
Coconut Grove
Morning Coffee and Networking in the Exhibit Hall
09:00
16 May 2025
Bimini
Recap of Day 1 and Topics Addressed on Day 2 of the Conference
Dr. Kristin Kopperud -- Co-Chair
Dr. Mike Roberts -- Co-Chair
09:15
16 May 2025
Bimini
Industry Success Stories -- Panel Discussion Chaired by Dr. Kristin Kopperud -- Conference Co-Chairperson and Science Program Director, ISS-National Laboratory
**Panelists**
Molly Mulligan, Redwire, Inc.
Tobias Niederwieser, BioServe
Alain Berinstain, CSS Inc.
10:00
16 May 2025
Bimini

Lisa Larkin, Professor, University of Michigan
Muscles in Microgravity: Pioneering Space Technology to Combat Aging
This presentation will discuss our journey to the final frontier of biological science as we team up with Space Tango to launch a cutting-edge tissue culture system to the International Space Station (ISS)! This presentation will discuss our efforts to deploy a 3-D innervated skeletal muscle construct within a meticulously engineered 12-well culture system designed by Space Tango. This innovative experiment is set to advance our understanding of muscle physiology under the unique conditions of microgravity. Equipped with the latest in biotechnology, our system will be designed to rigorously monitor the stability of muscle innervation, actively measure reactive oxygen species (ROS) activity, and assess the integrity of the neuromuscular junction (NMJ). With precise controls for media exchange, temperature regulation, oxygen supply, and advanced stimulation protocols, we will ensure the viability and accurate monitoring of our tissue constructs in the harsh environment of space. This research not only promises to deepen our insight into the mechanisms of muscle atrophy observed in both microgravity and aging but also propels us closer to developing targeted therapies for sarcopenia and other muscle-related diseases. This presentation will share insights from our preparatory work with Space Tango—highlighting the challenges and triumphs of gearing up to send viable biological specimens to the ISS.
10:30
16 May 2025
Coconut Grove
Mid-Morning Coffee Break and Networking in the Exhibit Hall
11:00
16 May 2025
Bimini

Molly Mulligan, Director, Business Development, Redwire, United States of America
Industry Success Stories: Biomanufacturing in Microgravity – Where we are Today and Where we Plan to Go in the Future
Biomanufacturing at scale in space is not today but it will be in the future. Using 3D bioprinters and automated crystallization systems with real time data, biomanufacturing is poised to have a breakthrough in microgravity. This talk will focus on the technology and possibilities of today on ISS and what the future holds on CLDs for true scale biomanufacturing in small and large molecule crystallization and 3D bioprinting.
11:30
16 May 2025
Bimini

Yupeng Chen, Associate Professor, University of Connecticut, United States of America
A Nanomaterials Approach for Cartilage Tissue Engineering and Tissue Chips on Earth and In Space
Producing authentic cartilage is challenging, especially in space, where the absence of biomechanical loading in microgravity can lead to cartilage degeneration. This creates a more demanding environment for engineering cartilage or utilizing engineered cartilage in various applications, such as tissue chips. To address this challenge, we have developed a family of self-assembled scaffolds called Janus Base Nano-Matrix (JBNm). JBNm forms through the self-assembly of DNA-inspired nanotubes and extracellular matrix proteins. For the first time, we have demonstrated that JBNm can overcome the challenges of growing and maintaining authentic cartilage under microgravity by enhancing β-integrin activation, which promotes chondrogenesis while inhibiting hypertrophy and apoptosis. Ultimately, we successfully achieved cartilage tissue engineering in space. This approach has also been applied to improve cartilage regeneration and advance tissue chip applications both on Earth and in space.
12:00
16 May 2025
Bimini

Jamie Foster, Professor, University of Florida, United States of America
Colonization by Beneficial Microbes Help Mitigate the Harmful Effects of Spaceflight and Maintain Animal Health
This presentation will explore how the space environment can affect the colonization and interactions between animal tissues and beneficial microbes. Here, we show recent results of the UMAMI spaceflight mission that used the symbiotic association between the bobtail squid, Euprymna scolopes, and its bioluminescent partner, Vibrio fischeri as model system. The results suggest that beneficial microbes can colonize nascent epithelial cells in the space environment and help mitigate stress responses of the host as well as helping to shape and maintain homeostasis of the host tissue environment.
12:30
16 May 2025
Bimini

Ngan Huang, Associate Professor, Department of Cardiothoracic Surgery, Stanford University, USA
Engineered Muscle Tissue in Microgravity As a Drug Screening Platform for Impaired Muscle Regeneration
Skeletal muscle undergoes impaired muscle regeneration and atrophy with progressive aging. Given the unique qualities of microgravity to accelerate the aging and muscle disuse process, we hypothesized that engineered skeletal muscle in microgravity mimics salient aspects of muscle aging and impaired regeneration. Here we describe the work of our recently completed Cardinal Muscle project to characterize the transcriptomic and proteomic effects of microgravity on muscle regeneration. We further demonstrate the feasibility of our muscle-on-a-chip platform for proof-of-concept drug screening to counteract microgravity effects. We will also discuss ongoing studies to expand drug screening efforts in an upcoming launch.
13:00
16 May 2025
Atrium
Networking Lunch
14:00
16 May 2025
Bimini

Palaniappan Sethu, Professor of Medicine and Biomedical Engineering, University of Alabama at Birmingham, United States of America
Streptococcus Pneumoniae (Spn) Infection of Cardiac Tissue in Space
There is evidence that the space environment enhances bacterial virulence, increases proliferation and promotes biofilm formation, potentially leading to more severe infection. Spn is a Gram-positive bacterium and the leading cause of community-acquired pneumonia; it is responsible for as many as 40% of all cases. There is strong evidence indicates that during severe community-acquired pneumonia, Spn gains access to and causes long-lasting damage in vital organs such as the heart, where Spn is now recognized to kill cardiomyocytes, form microlesions (biofilms within the cardiac tissue), impair heart function, and, in surviving animals, prime permanent cardiac scarring and impaired contractility. This talk will focus on the unique opportunity to leverage the space environment, which promotes cardiac tissue atrophy, enhances bacterial virulence and decreases susceptibility of bacteria to antimicrobial treatment to create an accelerated and more severe model of Spn infection of cardiac tissue. By exacerbating the infection process, we will amplify the molecular changes (gene expression, soluble factor production) involved in critical events that promote microlesion formation and enhance Spn virulence to understand molecular mechanisms and identify therapeutic targets for early intervention to prevent adverse cardiac events.
14:30
16 May 2025
Bimini

Tammy Chang, Professor of Surgery, University of California-San Francisco, United States of America
Liver Tissue Engineering in Space
Severe liver dysfunction is a leading cause of morbidity and mortality, and the only current treatment is liver transplantation. The critical shortage of donor organs limits the effectiveness of liver transplantation as a treatment modality. This unmet medical need has spurred intense research to develop alternative approaches, including differentiating hepatocytes from human stem cells as sources for functional tissue replacement therapy. Research from Dr. Chang’s laboratory has shown that microgravity facilitates the self-assembly of induced pluripotent stem cell (iPSC)-derived liver organoids that exhibit superior function compared to organoids generated by gravity-restricted methods on Matrigel. Sustained high-quality microgravity may be a key tool for developing large, vascularized tissues for use in clinical treatment of severe liver dysfunction. Accordingly, Dr. Chang’s laboratory is developing advanced supercooling tissue preservation approaches to enable robust bidirectional transport of biological matter between Earth and low Earth orbit (LEO), a capability critical for implementing biomanufacturing in LEO at scale.
15:00
16 May 2025
Bimini
Armin Rad
Title to be Confirmed
15:30
16 May 2025
Coconut Grove
Mid-Afternoon Coffee Break and Networking in the Exhibit Hall
16:00
16 May 2025
Bimini

Kristin Kopperud, Science Program Director, Biological Sciences, International Space Station National Laboratory, USA -- Conference Co-Chairperson
Session Sub-Title: Presentations from the Various Stakeholders in the Space Field
Presentation Title: Low Earth Orbit Research Opportunities on the International Space Station
I will provide an overview of the ISS National Laboratory, including its mission, role, and unique set of experimental conditions. I will also discuss some research opportunities, from past to upcoming, that are available to researchers desiring to conduct experiments in microgravity.
16:20
16 May 2025
Bimini

Emmanuel Urquieta, Vice Chair of Aerospace Medicine / Department of Medicine University of Central Florida College of Medicine, United States of America
Pioneering Aerospace Medicine: UCF’s Vision for Innovation in Space Health and Exploration
The University of Central Florida (UCF) College of Medicine has launched an innovative Aerospace Medicine Program, aiming to become a global leader in aerospace medicine research, education, clinical services, and training. Built on a multidisciplinary framework that engages expertise from all 13 UCF colleges, the program focuses on three primary areas: education, research, and collaboration with commercial spaceflight partners. In education, the program is developing groundbreaking initiatives, including an aerospace medicine elective for medical students and biomedical engineers, a Master’s of Science in Aerospace Medicine, and an ACGME-accredited Aerospace Medicine Residency. Additionally, it is establishing a fully capable FAA Aviation Medicine Clinic. In research, the program is creating platforms to support NASA and commercial spaceflight, such as a space medicine integration and testing facility to simulate missions with time-delayed communications and environmental controls, as well as a space medicine ultrasound and imaging facility to advance mission autonomy and miniaturized imaging technologies. The program also seeks to strengthen ties with commercial spaceflight companies, developing clinical and research facilities, biobanks, and capabilities near U.S. orbital launch and landing sites. Positioned strategically and bolstered by multidisciplinary expertise, this program addresses the evolving needs of aerospace medicine, laying the groundwork for future advancements in space exploration and commercial spaceflight.
16:40
16 May 2025
Bimini

Rihana Bokhari, Scientific Research Director at the Translational Research Institute for Space Health (TRISH), USA
SENTINEL: Advancing Remote, Autonomous Tissue Chip Systems for Research and Individualized Countermeasures
NASA’s Artemis missions will place astronauts in the lunar vicinity where they will experience deep space exposure on par with the Apollo missions, eventually far exceeding the prior experience. The Science ENterprise to INform Exploration Limits (SENTINEL) initiative is the TRISH effort to build automated microphysiological systems (MPS; also known as 3D tissues, tissue-on-a-chip or organ-on-a chip) that also have in-line sensing capabilities to self-regulate and provide data to the astronaut crew and scientists on the ground thus overcoming the need to return samples to Earth for analysis.
These MPS constructs have the potential to address several knowledge gaps in the impacts of the deep space environment. These systems can also be built as single organs or as systems of organs allowing for interactions to simulate responses that might occur within the human body in space. Successful research and technology development in this area will improve the capability to test the effects of the realistic, deep space radiation environment on a tissue as well as the impacts of medications or other interventions. These MPS would enable researchers to conduct time-course, mechanistic and countermeasure development studies while the MPS remain in space.
TRISH is working to advance these state-of-the-art platform capabilities and move towards autonomous systems. In the future, these tissue chips could be utilized for personalized medicine: with a customized tissue chip of an individual astronaut, sent into deep space before or with an astronaut, thus assisting in the overall assessment of the risks of the space environment on that individual's physiology. The end goal of the SENTINEL initiative is to provide the space life science research community with effective and reliable tools to preserve astronauts’ health span and ensure a performance-ready state during and after the mission.
17:00
16 May 2025
Bimini

Matthew Strickland, Medical Oncologist, Director of Translational Research, Center for Space Medicine Research, MGH-Harvard Medical School, USA
Title to be Confirmed
17:20
16 May 2025
Bimini

Alain Berinstain, Chief Strategy Officer, CSS Inc., United States of America
A New Bioreactor for Space being developed by CSS and Stamm
CSS is developing a new, scalable, and flexible bioreactor for space, based on proven terrestrial biomanufacturing technology developed by Stamm. Its flexibility allows for biomanufacturing or bioprocessing, cell culture, and drug testing using either prokaryotic or eukaryotic organisms. This new bioreactor allows for continuous culture (up to 90 days), uses laminar flow in liquid-tight, gas-permeable microchannels, and is bubble-free. The bioreactor core can be as small as 5mL and it is scalable to Liters, even thousands of Liters in the future. CSS will fly an initial bioreactor system to ISS for proof of concept and is in discussions for deployment on commercial platforms of the future. Use cases for applications of the technology are being sought, and we look forward to sharing this information with the SelectBio audience and receive feedback.
17:40
16 May 2025
Close of Conference